Our R&D Center
Empowering Breakthroughs from Molecule to Medicine
At Priosh PharmaChem AG, our commitment to research and development (R&D) is at the heart of everything we do. With a team of seasoned scientists and industry experts, we strive to innovate and enhance pharmaceutical solutions that address the ever-evolving needs of the healthcare landscape.
By investing in research, we are dedicated to delivering effective, safe, and sustainable therapies that improve patient outcomes worldwide.
Synthetic and Medicinal Chemistry
Our synthetic and medicinal chemistry capabilities are designed to facilitate rapid progression from concept to clinical application.
We specialize in...
- Route Design: Developing efficient synthetic pathways tailored to meet project specifications.
- Custom Synthesis: Providing bespoke synthesis of compounds to meet specific research needs.
- Parallel Synthesis: Enabling simultaneous synthesis of multiple compounds to accelerate research timelines.
- Library Design and Synthesis: Creating diverse compound libraries for high-throughput screening.
- Complex Chemistries: Handling challenging reactions, including the synthesis of phthalocyanine, peptides and polysaccharides.
Our team of chemists employs state-of-the-art techniques to optimize synthetic processes, ensuring quality and scalability.
Chemical Process R&D
Priosh is equipped to tackle complex chemical process challenges.
Our Chemical Process R&D focuses on:
- Process Optimisation: Streamlining synthesis routes to enhance efficiency and yield.
- Rapid Route Scouting: Quickly identifying viable synthetic pathways for new compounds.
- Scale-up Capabilities: Transitioning from laboratory-scale processes to commercial production seamlessly.
By leveraging our expertise in chemical engineering, we aim to enhance productivity while maintaining the highest quality standards in our manufacturing processes.
Kilo Lab and Small Scale Manufacturing
Our kilo lab and small-scale manufacturing capabilities are essential for early-stage development and feasibility studies.
We offer...
- Non-GMP Production: Facilitating initial batches for research purposes, including toxicity studies and formulation development.
- c-GMP Manufacturing: Ensuring compliance with current Good Manufacturing Practices for clinical trial supplies.
- Flexibility in Scale: Supporting projects that range from milligrams to several kilograms, allowing for efficient development without technology transfer hurdles.
This approach provides our clients with a rapid path to clinical trials, ensuring that valuable time and resources are optimized
Pre-Formulation Studies
Our pre-formulation studies are critical in understanding the properties of active pharmaceutical ingredients (APIs) and their behavior in formulations.
Key aspects include:
- API Characterisation: Conducting solubility studies, particle size analysis, polymorphism assessments, and stability studies.
- Drug-excipient Compatibility Studies: Evaluating the interaction between APIs and excipients to ensure formulation efficacy.
- Selection of Appropriate Packaging Material: Identifying optimal packaging solutions that maintain product integrity.
These studies serve as the foundation for successful formulation development, enabling us to create effective pharmaceutical products.
Formulation Capabilities
Priosh offers a comprehensive range of formulation capabilities.
Including...
- Oral Solids: Development of immediate and modified release tablets and capsules, bilayer tablets, and fixed-dose combinations.
- Oral Liquids: Formulation of solutions and suspensions designed for optimal bioavailability.
- Injectables: Expertise in formulating simple and complex injectables, including lyophilized products and nanoparticles.
- Peptides/Polypeptides/Proteins: Specializing in the formulation of biologics, ensuring stability and effectiveness.
Our formulation scientists employ the latest technologies and methodologies to develop market-ready pharmaceutical products
Analytical Capabilities
Analytical capabilities are integral to our R&D process.
We offer...
- Routine Analysis: Conducting extensive testing to ensure product quality and compliance with regulatory standards.
- Method Development and Validation: Creating and validating analytical methods tailored to specific product requirements.
- Stability Studies: Assessing the stability of formulations over time to ensure product efficacy throughout its shelf life.
- Technology Transfer: Facilitating the transfer of analytical methods and processes from R&D to manufacturing.
Our robust analytical framework ensures that every product meets the highest standards of quality and safety.
Technology Transfer
At Priosh, technology transfer is a vital aspect of our R&D process.
We focus on...
- Seamless Transition: Ensuring that processes developed in R&D can be efficiently scaled for manufacturing.
- Collaborative Partnerships: Working closely with our clients to align development and production goals.
- Documentation and Training: Providing comprehensive documentation and training to facilitate smooth transitions.
This commitment to effective technology transfer enhances project timelines and ensures consistent product quality.